(HealthDay)—Taking proton pump inhibitors (PPIs) is associated with an excess of cause-specific mortality, according to a study published online May 30 in The BMJ. Yan Xie, M.P.H., from St. Louis Health Care System, and colleagues conducted a longitudinal observational cohort study to estimate all-cause mortality and cause-specific mortality among patients taking PPIs. Data were included […]
Statin use reduces dementia risk after concussion in seniors
(HealthDay)—Older adults have an increased risk for dementia after concussion, which is modestly reduced among patients using a statin, according to a study published online May 20 in JAMA Neurology. Donald A. Redelmeier, M.D., from the University of Toronto, and colleagues examined whether statin use is associated with the risk for dementia after a concussion. […]
Mindfulness helps mothers with opioid use disorder combat depression
Mothers with opioid use disorder face many challenges as they work towards a more stable life for themselves and their children, depression not least among them. But medical interventions for depression can interfere with treatments for opioid addiction. New research from Jefferson (Philadelphia University + Thomas Jefferson University) shows that participation in a mindfulness-based parenting […]
Researchers find widely ‘inconsistent’ use of antibodies in lab experiments
Scientists at the Johns Hopkins Kimmel Center say they have affirmed widespread inconsistencies in the use of a common laboratory procedure called immunohistochemical staining, and say the variations are making many laboratory experiments unreliable. Their findings were outlined in a special issue of the Asian Journal of Urology. In a review of papers published about […]
Leukocytes use their nucleus as a ruler to choose path of least resistance
How do mobile cell types like leukocytes or metastatic cancer cells reach their place of action during immune surveillance or cancer dissemination, respectively? The research group around Michael Sixt at IST Austria has now shown that leukocytes use their nucleus as a ruler to screen their surroundings for the largest pores—and thereby find the path […]
Surge in cannabis use among youth preceded legalization in Canada
National discussions on cannabis legalization, along with increased access to medical marijuana, may have encouraged more high school students to consume the drug years before it became legal in Canada. A recent study using data from more than 230,000 questionnaires by Canadian high school students in grades 9 to 12 found that almost 10 per […]
Antibiotics: we’ve found faster, better way to identify the right one to use
Bacterial infections are best dealt with rapidly, but lab tests to determine the type of infection a patient has are slow. So if a doctor suspects a bacterial infection, she will probably prescribe a broad-spectrum antibiotic. In other words, an antibiotic that kills a wide range of disease-causing bacteria. It’s a buckshot approach rather than […]
Appropriate use criteria released for peripheral artery intervention
(HealthDay)—Appropriate use criteria have been developed for peripheral artery intervention (PAI) in peripheral artery disease, according to a report published online Dec. 17 in the Journal of the American College of Cardiology. Steven R. Bailey, M.D., from the University of Texas Health Science Center at San Antonio, and colleagues address appropriate use criteria in the […]
Study explores timing of muscle-related problems of statin use
Statins have been linked with muscle pain and other musculoskeletal adverse events (MAEs) in some patients. A new Pharmacology Research & Perspectives study has examined the timing of MAEs that develop during statin therapy and determined whether concomitant drugs used concurrently with statin therapy shifts the timing of MAEs. For the study, cases in which […]
Teens at High-Performing Schools Less Likely to Use Pot
WEDNESDAY, Oct. 31, 2018 — The type of high school teens attend may determine whether they’ll try marijuana and other illegal drugs, a new study suggests. “We concluded that schools play an important role in influencing adolescent behavior,” said study first author Dr. Rebecca Dudovitz, an assistant professor at the University of California, Los Angeles […]