A reader recently asked me to explain what’s meant by overdiagnosis. I wasn’t surprised because it (and overtreatment) is the buzz word of the moment in medical circles. For the avoidance of doubt here’s the definition of overdiagnosis. It’s the diagnosis of a condition that, if unrecognised, wouldn’t cause symptoms or harm a patient. The […]
Epigenetic therapy worth pursuing in hormone receptor positive advanced breast cancer
Epigenetic therapy with histone deacetylase (HDAC) inhibitors is worth pursuing in hormone receptor positive advanced breast cancer, suggests a phase III trial reported today at the ESMO 2018 Congress in Munich. Endocrine therapies are the foundation of treatment for patients with hormone receptor positive breast cancer. However, resistance to endocrine therapy is common, leading to […]
Ohio boy feted by town with early Christmas dies of brain cancer
Vandals try to ruin holiday cheer for terminally ill boy 2-year-old Brody Allen, from Ohio, loved seeing Christmas lights during his first holiday season last year so much that his family and town are putting up Christmas decorations early so the toddler can celebrate the holiday one last time. But in a disheartening turn of […]
First immunotherapy success for triple-negative breast cancer
There is new hope for people with an aggressive type of breast cancer, as an immunotherapy trial shows for the first time that lives can be extended in people with triple-negative breast cancer. New research led by Queen Mary University of London and St Bartholomew’s Hospital has shown that by using a combination of immunotherapy […]
Cancer: Could a ‘universal’ blood test make detection easier?
Cancer is one of the leading causes of death worldwide. According to the American Institute for Cancer Research, there were about 18 million cancer cases diagnosed around the world in 2018. The number of new cancer cases per year is expected to reach more than 23 million by 2030. The most common cancers globally are […]
How an idea from a lab may change cancer treatments
In recent years, researchers have begun to fight cancer by genetically engineering a patient’s own immune system to target the disease. Quad Technologies, a company that grew out of a Northeastern research lab, has been developing technology to facilitate this process. This summer, Quad Technologies was acquired by a global life sciences company that will […]
Mira Sorvino Discusses Metastatic Breast Cancer & the Connection With #MeToo
Pin Mira Sorvino frequently lends her voice to causes that help other people, whether it’s serving as an U.N. goodwill ambassador to combat human trafficking or speaking out on behalf of people who have experienced sexual violence via the #MeToo movement. In addition, the Academy Award-winning actor has also teamed up with #MoreForMBC: A campaign […]
Cancer rates spiral in Ladakh due to UV rays, sedentary lifestyle
The rough terrain, the snow-capped peaks, the winding roads and monasteries – the Ladakh region of Jammu and Kashmir is the abode of nature’s raw and untouched beauty. The region might be a haven for adventure travellers, but all is not well for the local residents. The high altitude, exposure to excessive ultraviolet (UV) rays, […]
AI model takes us closer to personalised cancer treatments
The ‘holy grail’ of cancer treatment: Scientists take a huge step towards personalised therapies after developing an AI model that predicts how tumours will respond to drugs Could help doctors identify the best treatment and drug dose for each patient The model may be available on the NHS in as little as 10 years time […]
New model mimics human tumors for accurate testing of cancer drugs
Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]