Nasopharyngeal carcinoma, NPC, is a rare tumor of the head and neck, which originates in the nasopharynx at the very back of the nose. NPC has a particularly high incidence in southern China, Southeast Asia, and North and East Africa and is rare in the rest of the world. Little is known about its etiology […]
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New insights into actions of insulin and their potential impact in treating diabetes
Insulin is one of the most well known hormones in the human body for its role in regulating blood glucose. While its absence or inaction causes diabetes (Type-I and Type-II), it is also associated with several metabolic disorders such as obesity, hypertension, cancer and aging. Levels of insulin, produced by the pancreas, fluctuate between fasted […]
Remarkable new insights into the pathology of Usher syndrome
Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses. For some 25 years now, the research group led by Professor Uwe Wolfrum of the Institute of Molecular Physiology at Johannes Gutenberg University Mainz […]
New insights into soft tissue injuries around the elbow joint
In his Ph.D. study, Toni Luokkala investigated the soft tissue injuries related to elbow collateral ligaments and distal biceps tendon tears. The elbow is the second most commonly dislocated joint after the glenohumeral joint. The extent of soft tissue injuries has an effect on the choice of treatment, rehabilitation and prognosis. Instability of the elbow […]
Dallas Heart Study yields new insights about depression
Recently published UT Southwestern research reveals new insights about risk factors for depression based on data from a landmark longitudinal study focused on heart disease. One study, published in the Journal of Clinical Psychiatry, shows a link between an inflammatory molecule in the blood and a person’s likelihood of depressive symptoms. The other study, in […]
New insights on a common protein could lead to novel cancer treatments
A new University of Colorado Boulder-led study sheds light on a protein key to controlling how cells grow, proliferate and function and long implicated in tumor development. The findings, published this week in the journal Genes and Development, could lead not only to new therapies for hard-to-treat cancers, but also inform novel treatments for neurological […]
Focus on COVID-19 deaths in under-65s for better insights into infection rates across populations, say researchers
Simply comparing the total number of deaths across countries may provide a misleading representation of the underlying level of transmission of SARS-CoV-2, the virus that causes COVID-19, because of large differences in reported COVID-19 death rates in elderly populations in different countries. The research, conducted by scientists at the University of Cambridge and the Institut […]
Towards better anti-cancer drugs: New insights into CDK8, an important human oncogene
Most cancers are caused by a large variety of factors that vary from one person to another. To unravel this complexity, genes that contribute to the development of a respective cancer must be identified. Such genes are called oncogenes. A good example of an oncogene is CDK8: Cyclin-dependent kinase 8. Misregulated CDK8 is an important […]
Biochemists discover new insights into what may go awry in brains of Alzheimer’s patients
More than three decades of research on Alzheimer’s disease have not produced any major treatment advances for those with the disorder, according to a UCLA expert who has studied the biochemistry of the brain and Alzheimer’s for nearly 30 years. “Nothing has worked,” said Steven Clarke, a distinguished professor of chemistry and biochemistry. “We’re ready […]
Research reveals new insights into how brain functions
For most native English-speakers, learning the Mandarin Chinese language from scratch is no easy task. Learning it in a class that essentially compresses a one-semester college course into a single month of intensive instruction—and agreeing to have your brain scanned before and after—might seem even more daunting. But the 24 Americans who did just that […]