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The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7. Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by overproduction of oxalate by the liver, leading to progressive kidney disease. In the ILLUMINATE-C phase 3 study, patients […]
Alstrom syndrome has been the focus of attention, among other ciliopathies, in research on the biological functions of cilia as well as the best mode of treatment of these disorders. The ALMS1 gene has been associated with this condition. Physiological Roles of ALMS1 Protein The ALMS1 gene has been the locus of research because of […]
A new artificial intelligence-based algorithm may help clinicians predict which patients with COVID-19 face a high risk of developing acute kidney injury (AKI) requiring dialysis. The research will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. Preliminary reports indicate that acute AKI is common in patients with COVID-19. Using data from […]
Researchers previously demonstrated that online peer mentoring for individuals with chronic kidney disease (CKD) improves patient activation—or patients’ willingness and ability to take actions to manage their health and care—and quality of life (QOL). Now the investigators have looked at the correlation between QOL and patient activation among patients with CKD who participated in an […]
Dapagliflozin reduces the risk of kidney failure, death from cardiovascular causes or heart failure hospitalization, and all-cause mortality in chronic kidney disease patients with or without type 2 diabetes. That’s the main result of the DAPA-CKD trial presented in a Hot Line session today at ESC Congress 2020. The DAPA-CKD trial tested the hypothesis that […]
Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma in patients with metastatic disease. Researchers from Dana-Farber Cancer Institute report a response rate of 24 percent across all risk categories of patients given an oral first-in-class agent that targets hypoxia inducible factor (HIF) 2-a, […]
Acute kidney injury (AKI) is common and it happens fast. Unlike chronic kidney disease, which often takes years to manifest, patients with AKI experience a rapid deterioration of kidney function over hours or days. Critically ill patients and those undergoing procedures that may affect the kidneys, such as coronary angiography or cardiac surgery, are at […]
Surgeons remove ‘the largest ever KIDNEY’ weighing 16lbs from a 56-year-old man in India after they found it swollen and covered with cysts Medics at Sir Ganga Ram Hospital in New Delhi spent two hours removing organ A healthy kidney weighs between 125g to 170g in men – less than half a pound Patient suffering […]
Supplements of vitamin D and omega-3 fatty acids (often sold as fish oil) do not help people with type 2 diabetes stave off chronic kidney disease, according to findings from the largest clinical study to date of the supplements in this patient population. The paper was published Friday, Nov. 8, 2019, in JAMA and presented […]
The researchers used the most advanced genomic and proteomic technologies available to tease out their proteogenomic characteristics, defined as genetic makeup (genomics), chemical modifications to DNA (epigenomics), messenger RNA located in cells that serves as template to make proteins (transcriptomics), and proteins (proteomics) and their modification by phosphate group (phosphoproteomics), a modification known to regulate […]