Neuroendocrine cancer can manifest itself as many small tumors in a cluster in the small intestine. New research shows that, surprisingly, these tumors originate from different cells that have mutated independently. The finding that the tumors are not related, which has been published in Nature Communications, came about through a close collaboration among clinical and […]
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New multiple sclerosis treatments focused on inhibiting nerve cell damage
Research from a University of Saskatchewan (USask) College of Medicine team will help develop medications that can inhibit the nerve cell damage that occurs due to diseases such as multiple sclerosis (MS). The research team has modeled the mechanisms by which a specific cell protein, A1, causes damage to nerve cells, expanding on previous USask […]
Patients who miss multiple GP appointments stay missing from healthcare
Research into the healthcare journey shows that patients who miss appointments with their GP are also less likely to attend hospital outpatient appointments. Patients who missed more than two GP appointments (on average) per year, were at least three times more likely to miss outpatient appointments compared to those who missed no GP appointments. “Missingness” from outpatient mental health services was especially high and it was also associated with “irregular discharge” from in-patient care. However, the researchers were […]
Multiple immune reactions when transplanting cartilage into monkeys
Immune rejection is one of the biggest obstacles to cell therapy. To solve this problem, researchers have been investigating iPS cells that have been gene edited so that they can evade the immune system. While this concept is theoretically possible, there is limited evidence that it works in species resembling humans. A new study by […]
‘Patchwork’ tumors prevalent across multiple cancer types
Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analyzed the whole genomes of tumor samples from over 2,600 patients with different types of cancer. They identified a high prevalence of genetic diversity within individual tumors, which they further characterized. Their […]
Molecule with potential to treat multiple sclerosis passes toxicology testing in zebrafish
Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma. The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a […]
Could rising temperatures send more people with multiple sclerosis to the hospital?
As average temperatures around the globe climb, a preliminary study has found people with multiple sclerosis (MS) may expect worsening symptoms, enough to send them to the hospital more often. The preliminary study released today, March 2, 2021, will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 […]
Multiple simulations best for COVID-19 predictions
Computer modelling used to forecast COVID-19 mortality contains significant uncertainty in its predictions, according to a new study led by researchers at UCL and the CWI institute in the Netherlands. The authors of the study, performed for the Royal Society’s RAMP initiative for Rapid Assistance in Modelling the Pandemic, highlighted that however well constructed such […]
Virtual reality shows promise for early detection of multiple sclerosis balance problems
People with multiple sclerosis (MS) often have a greatly increased risk of falling and injuring themselves even when they feel they’re able to walk normally. Now a team led by scientists from the UNC School of Medicine has demonstrated what could be a relatively easy method for the early detection of such problems. The researchers, […]
Brain activity patterns linked with improved learning and memory in multiple sclerosis
A recent article by Kessler Foundation researchers demonstrated g people with multiple sclerosis (MS). The article, “Brain activation patterns associated with paragraph learning in persons with multiple sclerosis: The MEMREHAB trial,” (doi: 10.1016/j.ijpsycho.2019.09.008 ) was epublished on October 20, 2019 by the International Journal of Psychophysiology. The authors are Olga Boukrina, Ph.D., Ekaterina Dobryakova, Ph.D., […]