Researchers in the Academic Unit of Neurology at Trinity College Dublin have identified characteristic changes in the patterns of electrical brain wave activity in motor neurone disease (MND). This ground breaking observation will help to develop treatments for the disease that affects over 350 people in Ireland. Their findings, published in the recent issue of […]
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Researchers compare visceral leishmaniasis diagnostic tests
Accurate and timely diagnosis of the tropic disease visceral leishmaniasis (VL) is one of the pillars for reducing VL deaths. Currently available serological tests for diagnosing VL vary widely in their performance and may, as a whole, be inadequate for VL diagnosis, researchers report in PLOS Neglected Tropical Diseases. Visceral leischmanisis is the most severe […]
Researchers describe new ALS biomarkers, potential new drug targets
Amyotrophic lateral sclerosis, or ALS, is an adult-onset neurodegenerative disease that causes paralysis and ultimately death when the nerves enervating the lungs cease to carry the signals needed for breathing. The disease has what is called a “focal onset,” where paralysis starts with an arm or a leg and spreads throughout the body as motor […]
Researchers link aging with changes in brain networks related to cognition
Functional regions within the brain become less distinct and interconnected in the elderly over time, especially in those networks related to attention span and cognition. The finding, published by researchers at Duke-NUS Medical School in The Journal of Neuroscience, adds to current understanding of longitudinal decline in brain network integrity associated with aging. “We currently […]
Researchers are using machine learning to screen for autism in children
For more than five years, researchers from Duke Engineering and the Duke University School of Medicine have been working toward creating an app that can help screen for autism in young children. With results from the first pilot study rolling in just last year, their work is leading to new insights about autism spectrum disorder […]
Researchers develop new blood test for faster, cheaper and more accurate detection of Alzheimer’s disease
Doctors may one day be able to diagnose Alzheimer’s disease (AD), the most common cause of severe dementia, and monitor a patient’s response to treatment by doing a simple blood test. This is made possible using the APEX (Amplified Plasmonic EXosome) system invented by researchers from the National University of Singapore (NUS). Designed to pick […]
Researchers explore the epigenetics of daytime sleepiness
Everyone feels tired at times, but up to 20 percent of U.S. adults report feeling so sleepy during the day that it interferes with daily activities, including working, having meals or carrying on conversations. Excessive daytime sleepiness (EDS) can lead to car accidents and work-related injuries and may increase risk of stroke and heart disease. […]
Researchers discover how three-dimensional organization of the genome regulates cell differentiation
A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation. Although the DNA sequence of the genome is a linear code, like a long sentence, the actual DNA molecule twists and folds in 3-D space, with some sequences […]
Researchers find widely ‘inconsistent’ use of antibodies in lab experiments
Scientists at the Johns Hopkins Kimmel Center say they have affirmed widespread inconsistencies in the use of a common laboratory procedure called immunohistochemical staining, and say the variations are making many laboratory experiments unreliable. Their findings were outlined in a special issue of the Asian Journal of Urology. In a review of papers published about […]
Gender identity leaves imprint on human brains, neuroscience researchers find
Society’s expectations about gender roles alter the human brain at the cellular level, according to a paper published by a group of neuroscience researchers at Georgia State University. “We are just starting to understand and study the ways in which gender identity, rather than sex, may cause the brain to differ in males and females,” […]